Power Amino Acids® and Factor4 Health
In Cardiovascular Health

George A. Scheele, M.D.


Cardiovascular Disease (CVD), including coronary heart disease (CHD) and stroke result from atherosclerotic plaques deposited in arteries that supply the heart and brain. For 200,000 people in the US every year, the first symptom of CVD is sudden death. CVD accounts for about half of all deaths and a large part of disability in our society. The costs of CVD are enormous and exceed $340 billion per year.

Cardiovascular disease is caused by atherosclerosis, which deposits lipid plaques in arteries throughout the body. The body responds to the lipid deposits by deploying the immune system in an attempt to clear the arterial plaques. This immune reaction increases C-Reactive Protein (CRP), which serves as a marker of inflammation in cardiovascular disease.

Cardiovascular disease is an integral part of the Metabolic Syndrome, which describes a spectrum of interrelated diseases, including obesity, type-2 diabetes, lipid disorders, and cardiovascular disease. The incidence of these diseases in the US is enormous and may be described as follows:


Disease Incidence
Overweight disorders 150 million
Obesity 75 million
High blood pressure 34 million
High cholesterol & TGL 30 million
High blood sugar 90 million
Type 2 Diabetes 30 million
Cardiovascular disease 57 million




Power Amino Acids® in Factor4 Weight Control® show beneficial effects in combating the chronic degenerative diseases associated with the Metabolic Syndrome as Factor4:

  • Normalizes body weight
  • Lowers blood sugar
  • Reduces LDL (bad) cholesterol
  • Elevates HDL (good) cholesterol
  • Improves the ratio of LDL/HDL in blood
  • Lowers blood pressure
  • Reduces C-Reactive Protein
  • Improves Cardiovascular Health



We have long suspected that Factor4 improves cardiovascular health based on the following indicators as Factor4 has been observed to:


  • Decrease both systolic and diastolic blood pressure
  •  Improve peripheral pulses, most notably those in the feet, including the dorsalis pedis and posterior tibial pulses
  •  Increase hair and nail growth which depends on both protein in the diet and improvements in vascular health associated with the scalp and nail bed.
  •  Improve skin color, which is directly related to vascular blood flow in epithelial surfaces.
  •  Combat neuropathies (loss of sensation) related to poor peripheral blood flow in the lower legs and feet
  • Combat neuralgias (burning sensations) related to poor peripheral blood flow in distal extremities




Peripheral neuropathies and neuralgias compromise driving and walking, where peripheral sensations are necessary for proper function. Hence older patients with these dysfunctions are well advised to avoid driving motor vehicles and to use a cane for assistance during walking.

In two notable patients, Factor4 has improved sensory functions dramatically in the legs and feet to the point where both were able to give up using a cane.


The “Sine Qua Non” of a healthy cardiovascular system is the absence of arterial blockages that impede the flow of blood to organs and tissues throughout the body. It has only been recently that we have observed quantitative data on blood flow through coronary and carotid arteries. In one notable case a 57 year old business man, Randy Newman, who owns a chain of 40 fast-food restaurants in Oklahoma, has asked all of his employees to take Factor4 in order to lose weight and improve their metabolic health.

Randy has a strong family history of overweight disorders, coronary heart disease and arterial blockages. At the time Randy started on Factor4 he weighed 300 pounds, suffered from profound fatigue and demonstrated a 28% blockage in one carotid artery in his neck. His coronary blood flow was also compromised.

Desperate for relief, Randy and his family took Factor4 aggressively four times a day with four scoops of powder per shake. Within two months Randy and his family recorded the following improvements in their metabolic health, which included:


  • An average weight loss of more than 20 pounds.
  • Decreases in systolic and diastolic blood pressure
  • Disappearance of their “sweet tooth,” which allowed them to avoid refined sugar, processed carbs and bread.
  •  A dramatic increase in energy
  •  Better sleep patterns with feelings of comfort, satisfaction and well-being throughout the day

But the height of Randy’s response was the improvements seen in his coronary and carotid blood flows. His coronary blood flow returned to normal for a 57 year old man. His 28% blockage in his carotid artery was reduced to less than 10%.

All of this improvement in cardiovascular health was documented within two months of taking Factor4 Weight Control. A video description of Randy Newman’s testimonial may be viewed here:



George A. Scheele, M.D.


Dr. Scheele is a world-renowned physician, inventor, author and two-time Nobel Associate, who has pioneered in understanding the critical role of amino acids in regulating metabolic health and body weight. He recently introduced Factor4 Weight Control® with essential ingredients to treat the four nutritional traps that lead to overweight disorders and obesity.

As a graduate of Princeton University and Johns Hopkins Medical School he served as Professors of Medicine on the faculties of The Rockefeller University, Yale University School of Medicine and Harvard Medical School. Dr. Scheele invented new concepts and techniques which “cracked the code” in understanding how Power Amino Acids® correct the deficiencies in amino acids, positive-charged proteins, and metabolic pathways that normalize body weight and restore metabolic health.

A pioneer in the development of the fields of Cell Biology and Molecular Biology and their impact on understanding chronic human diseases, he participated in work that won two Nobel Prizes in Medicine awarded in 1974 and 1999.

As a leader in nutritional science and medical research with 40 years of innovative scientific research and 10 years of breathtaking achievements in the fields of obesity and metabolic disease, Dr. Scheele’s passion has always been to “Make the World a Better Place”. After moving to La Jolla in 1998, he has utilized his vast experience to develop superior health-care products for individuals living in today’s fast-paced world.

Dr. Scheele is currently the Founder, President, and CEO of NovaLife, Inc. a San-Diego based biotech company that has pioneered in the development of innovative health-care products for people who suffer from obesity and metabolic diseases, including diabetes, lipid disorders, cardiovascular disease, autoimmune disorders, and aging.

Confidential Document: All rights reserved. No part of this document may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any other information storage and retrieval system, without the written permission of the publisher.

Disclaimer: This product is not meant to diagnose, treat, cure, or prevent any disease by the use of pharmaceutical drugs. As a dietary supplement, with all natural ingredients, considered to be “generally regarded as safe” (GRAS), Factor4 is intended only to improve health and wellness in the organs and tissues throughout the body. Comments and notations, derived from testimonials and limited human studies, have not been evaluated by the FDA. All results stated in this white paper and on our website(s) are actual results from real customers or individuals included in our clinical trials. Individual results may vary depending on personal goals and use.




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